Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells

Tpl2 Protects Against Fulminant Hepatitis Through Mobilization of Myeloid-Derived Suppressor Cells

Myeloid derived suppressor cells (MDSC) in the liver microenvironment protects against the inflammation-induced liver injury in fulminant hepatitis (FH). However, the molecular mechanism through which MDSC is recruited into the inflamed liver remain elusive. Here we identified a protein kinase Tpl2...

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Bibliographic Details
Main Authors: Jing Xu, Siyu Pei, Yan Wang, Junli Liu, Youcun Qian, Mingzhu Huang, Yanyun Zhang, Yichuan Xiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Immunology
Subjects:
hepatitis
myeloid-derive suppressor cells (MDSCs)
TPL2
IL-25
chemokine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01980/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01980/full

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