QSAR study and molecular docking of benzimidazole derivatives as potent activators of AMP-activated protein kinase
3D-QSAR and molecular docking methods were performed on a set of 74 benzimidazole derivatives previously studied as activators of the AMP-activated protein kinase (AMPK), a protein that plays a key role in the regulation of cellular energy balance. Relative enzyme activity (REA) of 74 compounds was...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2017-01-01
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| Series: | Journal of Taibah University for Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1658365516300279 |