SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy
<p>Abstract</p> <p>Cyclin D1 is an allosteric regulator for cyclin-dependent kinases 4 and 6 (CDK4/6). The cyclin D/CDK4 kinase promotes G1/S transition through the posttranslational modification and the subsequent inactivation of the retinoblastoma (Rb) protein and related family...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-01-01
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| Series: | Cell Division |
| Online Access: | http://www.celldiv.com/content/2/1/2 |