Defects in Polynucleotide phosphorylase impairs virulence in Escherichia coli O157:H7

Polynucleotide phosphorylase (PNPase) is reported to regulate virulence in Salmonella, Yersinia spp. and Campylobacter jejuni, yet its role in Escherichia coli O157:H7 has not been investigated. To gain insights into its roles in E. coli O157:H7 virulence, pnp deletion mutants were generated and the...

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Bibliographic Details
Main Authors: Jia eHu, Meijun eZhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-08-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00806/full