EFFECT OF INHIBITORS OF PROTEIN KINASE CK2 ON THE ACTIVITY ITS CATALYTIC SUBUNITS СК2α AND СК2α′
The effect of protein kinase CK2 inhibitors (with IC50 from 0.004 μM to 0.7 μM) from different chemical classes on the activity of СК2α and СК2α′ recombinant proteins has been studied. Biochemical tests shown that isozymes had different sensitivity toward the same compounds. The most isoform-selecti...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine.
2014-12-01
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| Series: | Biotechnologia Acta |
| Subjects: | |
| Online Access: | http://biotechnology.kiev.ua/images/storage/6_2014/ostrianskaia.pdf |