High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer

High Levels of Within-Host Variations of Human Papillomavirus 16 E1/E2 Genes in Invasive Cervical Cancer

Human papillomavirus type 16 (HPV16) is the most common HPV genotype found in invasive cervical cancer (ICC). Recent comprehensive genomics studies of HPV16 have revealed that a large number of minor nucleotide variations in the viral genome are present in each infected woman; however, it remains un...

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Bibliographic Details
Main Authors: Yusuke Hirose, Mayuko Yamaguchi-Naka, Mamiko Onuki, Yuri Tenjimbayashi, Nobutaka Tasaka, Toyomi Satoh, Kohsei Tanaka, Takashi Iwata, Akihiko Sekizawa, Koji Matsumoto, Iwao Kukimoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Microbiology
Subjects:
human papillomavirus
within-host variation
APOBEC
E1/E2
positive selection
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.596334/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2020.596334/full

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