Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis regulates breast cancer stemness via Wnt/β-catenin pathway

Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis regulates breast cancer stemness via Wnt/β-catenin pathway

Abstract Background The mechanism underlying breast cancer stem cell (BCSCs) characteristics remains to be fully elucidated. Accumulating evidence implies that long noncoding RNAs (lncRNAs) play a pivotal role in regulating BCSCs stemness. Methods LncRNA LUCAT1 expression was assessed in breast canc...

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Bibliographic Details
Main Authors: Ang Zheng, Xinyue Song, Lin Zhang, Lin Zhao, Xiaoyun Mao, Minjie Wei, Feng Jin
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Breast cancer
Stemness
LUCAT1
miR-5582-3p
Wnt/β-catenin signaling pathway
Online Access:http://link.springer.com/article/10.1186/s13046-019-1315-8

Internet

http://link.springer.com/article/10.1186/s13046-019-1315-8

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