Presenilin 2 overexpression is associated with apoptosis in Neuro2a cells

Presenilin 1 (PS1) and PS2 are evolutionarily conserved transmembrane proteins of the aspartyl protease family. Initially, they were reported to be associated with the early onset of familial, early-onset Alzheimer’s disease. PS1 has been implicated in several crucial brain functions including devel...

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Bibliographic Details
Main Authors: Kumar Ashish, Sivanandam T. M., Thakur M. K.
Format: Article
Language:English
Published: De Gruyter 2016-01-01
Series:Translational Neuroscience
Subjects:
p53
Online Access:https://doi.org/10.1515/tnsci-2016-0011