Presenilin 2 overexpression is associated with apoptosis in Neuro2a cells
Presenilin 1 (PS1) and PS2 are evolutionarily conserved transmembrane proteins of the aspartyl protease family. Initially, they were reported to be associated with the early onset of familial, early-onset Alzheimer’s disease. PS1 has been implicated in several crucial brain functions including devel...
Main Authors: | , , |
---|---|
Format: | Article |
Language: | English |
Published: |
De Gruyter
2016-01-01
|
Series: | Translational Neuroscience |
Subjects: | |
Online Access: | https://doi.org/10.1515/tnsci-2016-0011 |