Practical issues in imputation-based association mapping.

Imputation-based association methods provide a powerful framework for testing untyped variants for association with phenotypes and for combining results from multiple studies that use different genotyping platforms. Here, we consider several issues that arise when applying these methods in practice,...

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Bibliographic Details
Main Authors: Yongtao Guan, Matthew Stephens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-12-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2585794?pdf=render