Characterizing the heterogeneity of tumor tissues from spatially resolved molecular measures.

Tumor heterogeneity can manifest itself by sub-populations of cells having distinct phenotypic profiles expressed as diverse molecular, morphological and spatial distributions. This inherent heterogeneity poses challenges in terms of diagnosis, prognosis and efficient treatment. Consequently, tools...

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Bibliographic Details
Main Authors: John F Graf, Maria I Zavodszky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5708750?pdf=render