Effect of lumican on the migration of human mesenchymal stem cells and endothelial progenitor cells: involvement of matrix metalloproteinase-14.

Increasing number of evidence shows that soluble factors and extracellular matrix (ECM) components provide an optimal microenvironment controlling human bone marrow mesenchymal stem cell (MSC) functions. Successful in vivo administration of stem cells lies in their ability to migrate through ECM bar...

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Main Authors: Mariusz Malinowski, Katarzyna Pietraszek, Corinne Perreau, Mateusz Boguslawski, Véronique Decot, Jean-François Stoltz, Laurent Vallar, Jolanta Niewiarowska, Czeslaw Cierniewski, François-Xavier Maquart, Yanusz Wegrowski, Stéphane Brézillon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517548?pdf=render