Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit
<p>Abstract</p> <p>Aging and atherosclerosis are well-recognized risk factors for cardiac and neurovascular diseases. The Apolipoprotein E deficient (ApoE−/−) mouse on a high-fat diet is a classical model of atherosclerosis, characterized by the presence of atherosclerotic plaques...
Main Authors: | Badaut Jérôme, Copin Jean-Christophe, Fukuda Andrew M, Gasche Yvan, Schaller Karl, da Silva Rafaela F |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-06-01
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Series: | Journal of Neuroinflammation |
Subjects: | |
Online Access: | http://www.jneuroinflammation.com/content/9/1/132 |
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