Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

Increase of arginase activity in old apolipoprotein-E deficient mice under Western diet associated with changes in neurovascular unit

<p>Abstract</p> <p>Aging and atherosclerosis are well-recognized risk factors for cardiac and neurovascular diseases. The Apolipoprotein E deficient (ApoE−/−) mouse on a high-fat diet is a classical model of atherosclerosis, characterized by the presence of atherosclerotic plaques...

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Bibliographic Details
Main Authors: Badaut Jérôme, Copin Jean-Christophe, Fukuda Andrew M, Gasche Yvan, Schaller Karl, da Silva Rafaela F
Format: Article
Language:English
Published: BMC 2012-06-01
Series:Journal of Neuroinflammation
Subjects:
Neurovascular unit
Nitric oxide
Arginase
Blood brain barrier
Water channel
Brain aging
Online Access:http://www.jneuroinflammation.com/content/9/1/132

Internet

http://www.jneuroinflammation.com/content/9/1/132

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