Evidence for an Altered Tryptophan Metabolism in Fibromyalgia

Fibromyalgia (FM) is a prevalent syndrome with chronic pain and a hypothesized underlying disturbance of the tryptophan (TRP) metabolism. We performed a tryptophan depletion (TD) test in 17 FM patients and 17 controls. TRP, 5-hydroxyindoleacetic acid (5-HIAA), kynurenine (KYN), and interleukin-6 (IL...

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Main Authors: M.J. Schwarz, M. Offenbaecher, A. Neumeister, T. Ewert, M. Willeit, N. Praschak-Rieder, J. Zach, M. Zacherl, K. Lossau, R. Weisser, G. Stucki, M. Ackenheil
Format: Article
Language:English
Published: Elsevier 2002-12-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102905632