Functional Characterization of ABCC Proteins from Trypanosoma cruzi and Their Involvement with Thiol Transport

Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi and affects 8 million people worldwide. The main chemotherapy is based on benznidazole. The efficacy in the treatment depends on factors such as the parasite strain, which may present different sensitivity to treatment....

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Bibliographic Details
Main Authors: Kelli Monteiro da Costa, Raphael C. Valente, Eduardo J. Salustiano, Luciana B. Gentile, Leonardo Freire-de-Lima, Lucia Mendonça-Previato, José O. Previato
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
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Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00205/full

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