Functional Characterization of ABCC Proteins from Trypanosoma cruzi and Their Involvement with Thiol Transport
Chagas disease is a neglected disease caused by the protozoan Trypanosoma cruzi and affects 8 million people worldwide. The main chemotherapy is based on benznidazole. The efficacy in the treatment depends on factors such as the parasite strain, which may present different sensitivity to treatment....
Main Authors: | Kelli Monteiro da Costa, Raphael C. Valente, Eduardo J. Salustiano, Luciana B. Gentile, Leonardo Freire-de-Lima, Lucia Mendonça-Previato, José O. Previato |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2018-02-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/article/10.3389/fmicb.2018.00205/full |
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