A green microwave method for synthesizing a more stable phthalazin-1-ol isomer as a good anticancer reagent using chemical plasma organic reactions

Abstracts: Conventional synthesis of the phthalazine has already allowed affording the phthalazin-1-one phthalazin-1-ol dynamic equilibrium that decreases the anticancer activity due to diminishing the concentration of the phthalazin-1-ol product. Nowadays, pure phthalazin-1-ol (5) can be gaining by...

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Bibliographic Details
Main Authors: Sameh A. Rizk, Maher A. El-Hashash, Amr A. Youssef, Abdelfattah T. Elgendy
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402100325X