Collagen Organization Does Not Influence T-Cell Distribution in Stroma of Human Pancreatic Cancer

Collagen Organization Does Not Influence T-Cell Distribution in Stroma of Human Pancreatic Cancer

The dominant intrastromal T-cell infiltration in pancreatic cancer is mainly caused by the contact guidance through the excessive desmoplastic reaction and could represent one of the obstacles to an effective immune response in this tumor type. This study analyzed the collagen organization in normal...

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Bibliographic Details
Main Authors: Eva-Maria Kamionka, Baifeng Qian, Wolfgang Gross, Frank Bergmann, Thilo Hackert, Carlo A. Beretta, Nicolas Dross, Eduard Ryschich
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
human pancreatic cancer
collagen organization
T-cell infiltration
tumor stroma
chemokines
Online Access:https://www.mdpi.com/2072-6694/13/15/3648

Internet

https://www.mdpi.com/2072-6694/13/15/3648

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