GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia
Schizophrenia is a brain disorder associated with cognitive deficits that severely affect the patients' capacity for daily functioning. Whereas our understanding of its pathophysiology is limited, postmortem studies suggest that schizophrenia is associated with deficits of GABA-mediated synapti...
Main Authors: | Guillermo Gonzalez-Burgos, Kenneth N. Fish, David A. Lewis |
---|---|
Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2011-01-01
|
Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2011/723184 |
Similar Items
-
Prefrontal cortical alterations of glutamate and GABA neurotransmission in schizophrenia: Insights for rational biomarker development
by: Kirsten E. Schoonover, et al.
Published: (2020-12-01) -
Alterations in cortical interneurons and cognitive function in schizophrenia
by: Samuel J. Dienel, et al.
Published: (2019-11-01) -
Mapping synaptic pathology within cerebral cortical circuits in subjects with schizophrenia
by: Robert Sweet, et al.
Published: (2010-06-01) -
Control of cortical neuronal migration by glutamate and GABA
by: Heiko J Luhmann, et al.
Published: (2015-01-01) -
Deviant cortical sulcation related to schizophrenia and cognitive deficits in the second trimester
by: MacKinley Michael Lloyd, et al.
Published: (2020-07-01)