GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia

Schizophrenia is a brain disorder associated with cognitive deficits that severely affect the patients' capacity for daily functioning. Whereas our understanding of its pathophysiology is limited, postmortem studies suggest that schizophrenia is associated with deficits of GABA-mediated synapti...

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Bibliographic Details
Main Authors: Guillermo Gonzalez-Burgos, Kenneth N. Fish, David A. Lewis
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Neural Plasticity
Online Access:http://dx.doi.org/10.1155/2011/723184