GPER mediates cardiotropic effects in spontaneously hypertensive rat hearts.

Estrogens promote beneficial effects in the cardiovascular system mainly through the estrogen receptor (ER)α and ERβ, which act as ligand-gated transcription factors. Recently, the G protein-coupled estrogen receptor (GPER) has been implicated in the estrogenic signaling in diverse tissues, includin...

Full description

Bibliographic Details
Main Authors: Ernestina Marianna De Francesco, Tommaso Angelone, Teresa Pasqua, Marco Pupo, Maria Carmela Cerra, Marcello Maggiolini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23950890/?tool=EBI