Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis

Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis

Background/objectives: Accelerating the process of bone regeneration is of great interest for surgeons and basic scientists alike. Recently, umbilical cord mesenchymal stem cells (UCMSCs) are considered clinically applicable for tissue regeneration due to their noninvasive harvesting and better viab...

Full description

Bibliographic Details
Main Authors:	Yong Liu, Jiarui Fang, Quan Zhang, Xiaoguang Zhang, Yulin Cao, Wei Chen, Zengwu Shao, Shuhua Yang, Dongcheng Wu, Man Hung, Yingze Zhang, Wei Tong, Hongtao Tian
Format:	Article
Language:	English
Published:	Elsevier 2020-07-01
Series:	Journal of Orthopaedic Translation
Subjects:	Angiogenesis Bone regeneration Umbilical cord MSCs Wnt signalling pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S2214031X20300188

Similar Items

Multiple umbilical cord–derived MSCs administrations attenuate rat osteoarthritis progression via preserving articular cartilage superficial layer cells and inhibiting synovitis
by: Wei Tong, et al.
Published: (2020-07-01)

Trimetazidine Protects Umbilical Cord Mesenchymal Stem Cells Against Hypoxia and Serum Deprivation Induced Apoptosis by Activation of Akt
by: Xuhe Gong, et al.
Published: (2014-12-01)

Inhibition of Circulating miR-194-5p Reverses Osteoporosis through Wnt5a/β-Catenin-Dependent Induction of Osteogenic Differentiation
by: Bobin Mi, et al.
Published: (2020-09-01)

Intravenous infusion of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells as a potential treatment for patients with COVID-19 pneumonia
by: Yingxin Zhang, et al.
Published: (2020-05-01)

Mesangiogenic Progenitor Cells Are Tissue Specific and Cannot Be Isolated From Adipose Tissue or Umbilical Cord Blood
by: Serena Barachini, et al.
Published: (2021-07-01)

Human bone marrow mesenchymal stem cells-derived exosomes alleviate liver fibrosis through the Wnt/β-catenin pathway
by: Xiaoli Rong, et al.
Published: (2019-03-01)

EGFL6 regulates angiogenesis and osteogenesis in distraction osteogenesis via Wnt/β-catenin signaling
by: Junjie Shen, et al.
Published: (2021-07-01)

Significance of soluble growth factors in the chondrogenic response of human umbilical cord matrix stem cells in a porous three dimensional scaffold
by: RS Nirmal, et al.
Published: (2013-11-01)

The umbilical cord, preeclampsia and the VEGF family
by: Olaya-C M, et al.
Published: (2018-11-01)

An Overview on Mesenchymal Stem Cells Derived from Extraembryonic Tissues: Supplement Sources and Isolation Methods
by: Salehinejad P, et al.
Published: (2020-07-01)

Comparative separation methods and biological characteristics of human placental and umbilical cord mesenchymal stem cells in serum-free culture conditions
by: Xiao Yi, et al.
Published: (2020-05-01)

Wnt-Dependent Activation of ERK Mediates Repression of Chondrocyte Fate during Calvarial Development
by: Beatriz A Ibarra, et al.
Published: (2021-06-01)

¿Cuándo pinzar el cordón umbilical? When to clamp the umbilical cord?
by: Fernando Arango Gómez, et al.
Published: (2004-06-01)

Hematoma del cordón umbilical: a propósito de un caso interesante Umbilical cord hematoma: an interesting case
by: Angelicia Crespo Campos, et al.
Published: (2009-06-01)

Cyasterone accelerates fracture healing by promoting MSCs migration and osteogenesis
by: Junlang Zhu, et al.
Published: (2021-05-01)

A Multivessel Umbilical Cord with a Single Umbilical Artery
by: Subrat Panda, et al.
Published: (2013-07-01)

WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway
by: Jingcai Wang, et al.
Published: (2020-10-01)

Liver as Main Content of Hernia of Umbilical Cord
by: Parveen Kumar, et al.
Published: (2020-05-01)

Repair of alveolar cleft bone defects by bone collagen particles combined with human umbilical cord mesenchymal stem cells in rabbit
by: Xue-Cheng Sun, et al.
Published: (2020-08-01)

LncRNA KCNQ1OT1 promotes osteogenic differentiation to relieve osteolysis via Wnt/β-catenin activation
by: Xuren Gao, et al.
Published: (2018-03-01)

Umbilical Cord Coiling Index and Perinatal Outcome
by: Nivedita S. Patil, et al.
Published: (2013-08-01)

Umbilical cord-derived mesenchymal stem cells for COVID-19 patients with acute respiratory distress syndrome (ARDS)
by: G. Lanzoni, et al.
Published: (2020-04-01)

Incarcerated umbilical cord hernia containing the gallbladder
by: Ann M. Kulungowski, et al.
Published: (2017-06-01)

Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway
by: Rong-Hua Yu, et al.
Published: (2020-08-01)

Umbilical Coiling Index and Its Relationship with Perinatal Outcomes
by: SASWATI TRIPATHY
Published: (2014-04-01)

Single umbilical artery
by: Shanthi Ramesh, et al.
Published: (2015-01-01)

WNT16 is Robustly Increased by Oncostatin M in Mouse Calvarial Osteoblasts and Acts as a Negative Feedback Regulator of Osteoclast Formation Induced by Oncostatin M
by: Henning P, et al.
Published: (2021-09-01)

Congenital hernia of umbilical cord masquerading as umbilical cyst and omphalocele on antenatal scans
by: Krishna Revanna Gopagondanahalli, et al.
Published: (2020-01-01)

Ethical issues concerning a pay‐to‐participate stem cell study
by: Leigh Turner, et al.
Published: (2021-06-01)

Ectopic Pancreatic Tissue Presenting as an Umbilical Mass in a Newborn: A Case Report
by: Wei-Te Lee, et al.
Published: (2005-02-01)

Umbilicoplasty in children with huge umbilical hernia
by: Akakpo-Numado Gamedzi Komlatsè, et al.
Published: (2014-01-01)

¿Cuándo pinzar el cordón umbilical?
by: Fernando Arango Gómez, et al.
Published: (2004-06-01)

Umbilical endometriosis: a case series
by: Dorothy Makena, et al.
Published: (2020-09-01)

GOLPH3 Promotes Angiogenesis of Lung Adenocarcinoma by Regulating the Wnt/β-Catenin Signaling Pathway
by: Zhao C, et al.
Published: (2020-06-01)

A comparative study on the mechanical properties of the umbilical vein and umbilical artery under uniaxial loading
by: Alireza Karimi, et al.
Published: (2014-02-01)

The Era of Umbilical Cord Blood Transplantation and Banking
by: Md Jalilur Rahman, et al.
Published: (2010-07-01)

Dose-Response Tendon-Specific Markers Induction by Growth Differentiation Factor-5 in Human Bone Marrow and Umbilical Cord Mesenchymal Stem Cells
by: Maria Camilla Ciardulli, et al.
Published: (2020-08-01)

Rupture of Umbilical Hernia with Evisceration in a Newborn - A Case Report
by: Dinesh H Kittur, et al.
Published: (2017-08-01)

Icariin Ameliorate Thiram-Induced Tibial Dyschondroplasia via Regulation of WNT4 and VEGF Expression in Broiler Chickens
by: Hui Zhang, et al.
Published: (2018-02-01)

WNT3a and WNT5a Transported by Exosomes Activate WNT Signaling Pathways in Human Cardiac Fibroblasts
by: Edyta Działo, et al.
Published: (2019-03-01)

Cannot write session to /tmp/vufind_sessions/sess_qcdqc8jkgh0nlbeqo9dup4pia5