Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis

Wnt10b-overexpressing umbilical cord mesenchymal stem cells promote critical size rat calvarial defect healing by enhanced osteogenesis and VEGF-mediated angiogenesis

Background/objectives: Accelerating the process of bone regeneration is of great interest for surgeons and basic scientists alike. Recently, umbilical cord mesenchymal stem cells (UCMSCs) are considered clinically applicable for tissue regeneration due to their noninvasive harvesting and better viab...

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Bibliographic Details
Main Authors: Yong Liu, Jiarui Fang, Quan Zhang, Xiaoguang Zhang, Yulin Cao, Wei Chen, Zengwu Shao, Shuhua Yang, Dongcheng Wu, Man Hung, Yingze Zhang, Wei Tong, Hongtao Tian
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Journal of Orthopaedic Translation
Subjects:
Angiogenesis
Bone regeneration
Umbilical cord MSCs
Wnt signalling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X20300188

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http://www.sciencedirect.com/science/article/pii/S2214031X20300188

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