Adult pancreas side population cells expand after β cell injury and are a source of insulin-secreting cells.

Pancreas stem cells are a potential source of insulin-producing β cells for the therapy of diabetes. In adult tissues the 'side population' (SP) of cells that effluxes the DNA binding dye Hoechst 33342 through ATP-binding cassette transporters has stem cell properties. We hypothesised ther...

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Bibliographic Details
Main Authors: Ilia Banakh, Leonel J Gonez, Robyn M Sutherland, Gaetano Naselli, Leonard C Harrison
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3494669?pdf=render