In situ hexagonal liquid crystal for intra-articular delivery of sinomenine hydrochloride

In situ hexagonal liquid crystal for intra-articular delivery of sinomenine hydrochloride

The aim of this study was to investigate the release behaviors of sinomenine hydrochloride loaded via in situ hexagonal liquid crystal (ISH), and its potential to improve the local bioavailability in knee joints of sinomenine hydrochloride (SMH) after intra-articular administration. The ISH was prep...

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Bibliographic Details
Main Authors: Xiao Liang, Yulin Chen, Li Wu, Abi Maharjan, Balmukunda Regmi, Jiwen Zhang, Shuangying Gui
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
In Situ hexagonal liquid crystal
Sinomenine hydrochloride
Rheumatoid arthritis
Sustained release
Intra-articular administration
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219308947

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http://www.sciencedirect.com/science/article/pii/S0753332219308947

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