Identification of Genes Regulating Gene Targeting by a High-Throughput Screening Approach

Homologous gene targeting (HGT) is a precise but inefficient process for genome engineering. Several methods for increasing its efficiency have been developed, including the use of rare cutting endonucleases. However, there is still room for improvement, as even nuclease-induced HGT may vary in effi...

Full description

Bibliographic Details
Main Authors: Fabien Delacôte, Christophe Perez, Valérie Guyot, Catherine Mikonio, Pierrick Potrel, Jean-Pierre Cabaniols, Christophe Delenda, Frédéric Pâques, Philippe Duchateau
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.4061/2011/947212