Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage

Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage

Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of phospholipid unsatura...

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Bibliographic Details
Main Authors: Marco M Manni, Marion L Tiberti, Sophie Pagnotta, Hélène Barelli, Romain Gautier, Bruno Antonny
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
polyunsaturated phospholipid
Dynamin
membrane curvature
membrane fission
membrane permeability
omega-3 omega-6 PUFAs
Online Access:https://elifesciences.org/articles/34394

Internet

https://elifesciences.org/articles/34394

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