Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against <i>Clostridioides difficile</i>

Colonisation Factor CD0873, an Attractive Oral Vaccine Candidate against <i>Clostridioides difficile</i>

<i>Clostridioides difficile</i> is the main cause of health-care-associated infectious diarrhoea. Toxins, TcdA and TcdB, secreted by this bacterium damage colonic epithelial cells and in severe cases this culminates in pseudomembranous colitis, toxic megacolon and death. Vaccines in huma...

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Bibliographic Details
Main Authors: Cansu Karyal, Jaime Hughes, Michelle L Kelly, Jeni C. Luckett, Philip V Kaye, Alan Cockayne, Nigel P Minton, Ruth Griffin
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Microorganisms
Subjects:
mucosal immunity
sIgA
oral vaccination
<i>Clostridioides difficile</i>
colonisation factor
Online Access:https://www.mdpi.com/2076-2607/9/2/306

Internet

https://www.mdpi.com/2076-2607/9/2/306

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