Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1

Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1

Abstract Background Manganese superoxide dismutase (MnSOD) upregulating FoxM1 have previously been demonstrated promoting lung cancer stemness. Isovitexin exhibits antitumor activities in various cancers. This study aimed to assess whether isovitexin inhibits hepatic carcinoma stem-like cells (HCSLC...

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Bibliographic Details
Main Authors: Xiaocheng Cao, Lihua Liu, Qing Yuan, Xiang Li, Yinghong Cui, Kaiqun Ren, Chang Zou, A. Chen, Chang Xu, Yebei Qiu, Meifang Quan, Jiansong Zhang, Jianguo Cao, Xiangding Chen
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Hepatic carcinoma
Cancer stem cells
Isovitexin
MnSOD
FoxM1
Online Access:http://link.springer.com/article/10.1186/s13046-019-1244-6

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http://link.springer.com/article/10.1186/s13046-019-1244-6

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