Low expression of TRAF3IP2-AS1 promotes progression of NONO-TFE3 translocation renal cell carcinoma by stimulating N 6-methyladenosine of PARP1 mRNA and downregulating PTEN

Low expression of TRAF3IP2-AS1 promotes progression of NONO-TFE3 translocation renal cell carcinoma by stimulating N 6-methyladenosine of PARP1 mRNA and downregulating PTEN

Abstract Background NONO-TFE3 translocation renal cell carcinoma (NONO-TFE3 tRCC) is one subtype of RCCs associated with Xp11.2 translocation/TFE3 gene fusions RCC (Xp11.2 tRCCs). Long non-coding RNA (lncRNA) has attracted great attention in cancer research. The function and mechanisms of TRAF3IP2 a...

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Bibliographic Details
Main Authors: Lei Yang, Yi Chen, Ning Liu, QianCheng Shi, Xiaodong Han, Weidong Gan, Dongmei Li
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Journal of Hematology & Oncology
Subjects:
TRAF3IP2-AS1
M6A modification
NONO-TFE3
PARP1
PTEN
Online Access:https://doi.org/10.1186/s13045-021-01059-5

Internet

https://doi.org/10.1186/s13045-021-01059-5

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