The effects of B cell depletion on immune related adverse events associated with immune checkpoint inhibition

The effects of B cell depletion on immune related adverse events associated with immune checkpoint inhibition

Abstract This letter describes the potential effect of B cell depletion on immune related adverse events associated with immune checkpoint inhibition. B cell depleting agents such as rituximab reduce B cell to plasma cell differentiation and antibody production. This treatment strategy is used in se...

Full description

Bibliographic Details
Main Authors: Rasmus Strøm Risbjerg, Mie Vennize Hansen, Anne Sofie Sørensen, Tue Wenzel Kragstrup
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Experimental Hematology & Oncology
Subjects:
B cell depletion
Immune checkpoint inhibition
Immune related adverse events
Immune mediated inflammatory disease
Hypothyroidism
Online Access:http://link.springer.com/article/10.1186/s40164-020-00167-1

Internet

http://link.springer.com/article/10.1186/s40164-020-00167-1

Similar Items