Gold-containing compound BDG-I inhibits the growth of A549 lung cancer cells through the deregulation of miRNA expression

Gold complex bis(diethyldithiocarbamato-gold(I)) bis(diphenylphosphino) methane (BDG-I) is cytotoxic toward different cancer cell lines. We compared the cytotoxic effect of BDG-I with that of cisplatin in the A549 lung cancer cell line. Additionally, we investigated the molecular mechanism underlyin...

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Bibliographic Details
Main Authors: Ali Alhoshani, A. Alrashdi, Khaled Alhosaini, Fawaz E. Alanazi, Nehad M. Alajez, Muhammad Altaf, Anvarhusein A. Isab, Hesham M. Korashy
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:Saudi Pharmaceutical Journal
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016418301130