A robust platform for high-throughput screening of therapeutic strategies for acute and chronic spinal cord injury

Summary: Astrocytes and microglia are critical regulators of inflammatory cascade after spinal cord injury (SCI). Existing glial in vitro studies do not replicate inflammatory phases associated with SCI. Here, we report an in vitro model of mixed glial culture where inflammation is induced by the ad...

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Bibliographic Details
Main Authors: Vaibhav Patil, Enda O'Connell, Leo R. Quinlan, Howard Fearnhead, Siobhan McMahon, Abhay Pandit
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221001504