NR2B expression in rat DRG is differentially regulated following peripheral nerve injuries that lead to transient or sustained stimuli-evoked hypersensitivity

NR2B expression in rat DRG is differentially regulated following peripheral nerve injuries that lead to transient or sustained stimuli-evoked hypersensitivity

Following injury, primary sensory neurons undergo changes that drive central sensitization and contribute to the maintenance of persistent hypersensitivity. NR2B expression in the Dorsal root ganglia (DRG) has not been previously examined in neuropathic pain models. Here we investigated if changes...

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Bibliographic Details
Main Authors: Monica Norcini, Alexandra Sideris, Samantha M Adler, Lourdes A Martin Hernandez, Jin Zhang, Thomas J J Blanck, Esperanza Recio-Pinto
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Molecular Neuroscience
Subjects:
sensory neurons
neuropathic pain
dorsal root ganglia
DRG
NR2B
Spared nerve injury
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00100/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00100/full

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