Recombinant production and biochemical and in silico characterization of lactate dehydrogenase from Geobacillus thermodenitrificans DSM-465

Background: Lactate dehydrogenase (LDH) is an enzyme of glycolytic pathway, ubiquitously found in living organisms. Increased glycolysis and LDH activity are associated with many pathologic conditions including inflammation and cancer, thereby making the enzyme a suitable drug target. Studies on con...

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Bibliographic Details
Main Authors: Muhammad Shahid Nadeem, Maryam A. Al-Ghamdi, Jalaluddin Azam Khan, Saida Sadath, Abdulaziz Al-Malki
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Electronic Journal of Biotechnology
Online Access:http://www.sciencedirect.com/science/article/pii/S0717345818300289