Heart regeneration in the salamander relies on macrophage-mediated control of fibroblast activation and the extracellular landscape

Macrophages necessary for heart regeneration Heart regeneration in salamanders is dependent on the activation of immune cells. James Godwin of The Jackson Laboratory and MDI Biological Laboratory in the US and colleagues depleted all major organs of a group of Mexican salamanders of macrophages, an...

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Bibliographic Details
Main Authors: J. W. Godwin, R. Debuque, E. Salimova, N. A. Rosenthal
Format: Article
Language:English
Published: Nature Publishing Group 2017-07-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-017-0027-y