Molecular mechanisms creating bistable switches at cell cycle transitions

Progression through the eukaryotic cell cycle is characterized by specific transitions, where cells move irreversibly from stage i−1 of the cycle into stage i. These irreversible cell cycle transitions are regulated by underlying bistable switches, which share some common features. An inhibitory pro...

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Bibliographic Details
Main Authors: Anael Verdugo, P. K. Vinod, John J. Tyson, Bela Novak
Format: Article
Language:English
Published: The Royal Society 2013-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.120179