Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse

Inhibition of HMG CoA reductase reveals an unexpected role for cholesterol during PGC migration in the mouse

<p>Abstract</p> <p>Background</p> <p>Primordial germ cells (PGCs) are the embryonic precursors of the sperm and eggs. Environmental or genetic defects that alter PGC development can impair fertility or cause formation of germ cell tumors.</p> <p>Results</...

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Bibliographic Details
Main Authors: Ewing Andrew G, Porter Forbes D, Merkel Erin I, Dudley Brian, Nalepka Jennifer, Kurczy Michael, Jiang DeChen, Ding Jiaxi, Winograd Nicholas, Burgess James, Molyneaux Kathleen
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Developmental Biology
Online Access:http://www.biomedcentral.com/1471-213X/8/120

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http://www.biomedcentral.com/1471-213X/8/120

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