Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy

<p>Abstract</p> <p>Background</p> <p>Thymidylate synthase (TS) and Topoisomerase I (Topo I) are significant biomarkers in colorectal cancer (CRC). We aimed to study the expression of TS and Topo I in patients with resected CRC who received adjuvant chemotherapy and corr...

Full description

Bibliographic Details
Main Authors: Papakostas Pavlos, Kafiri Georgia, Pentheroudakis George, Xiros Nikolaos, Bobos Mattheos, Karina Maria, Karavasilis Vasilios, Kostopoulos Ioannis, Vrettou Eleni, Fountzilas George
Format: Article
Language:English
Published: BMC 2009-09-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/339