A Novel Variant of the FZD4 Gene in a Chinese Family Causes Autosomal Dominant Familial Exudative Vitreoretinopathy

A Novel Variant of the FZD4 Gene in a Chinese Family Causes Autosomal Dominant Familial Exudative Vitreoretinopathy

Background/Aims: Familial exudative vitreoretinopathy (FEVR) is a complex hereditary eye disorder characterized by incomplete development of the retinal vasculature, thereby affecting retinal angiogenesis. Methods: In this study, a Chinese autosomal dominant FEVR pedigree was recruited. Ophthalmic e...

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Bibliographic Details
Main Authors: Lisha Yang, Jiewen Fu, Jingliang Cheng, Chunli Wei, Qi Zhou, Iqra Ijaz, Hongbin Lv, Junjiang Fu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Familial exudative vitreoretinopathy (FEVR)
FZD4 gene
Missense mutation
Targeted next-generation sequencing
Expression
Online Access:https://www.karger.com/Article/FullText/495901

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https://www.karger.com/Article/FullText/495901

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