The role of chemokines in shaping the balance between CD4+ T cell subsets and its therapeutic implications in autoimmune and cancer diseases
Chemokines are the key activators of adhesion molecule and also drivers of leukocyte migration to inflammatory sites, and are therefore mostly considered as pro-inflammatory mediators. Many studies, including ours, imply that targeting the function of several key chemokines, but not many others, cou...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2015-11-01
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Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00609/full |