The role of chemokines in shaping the balance between CD4+ T cell subsets and its therapeutic implications in autoimmune and cancer diseases

Chemokines are the key activators of adhesion molecule and also drivers of leukocyte migration to inflammatory sites, and are therefore mostly considered as pro-inflammatory mediators. Many studies, including ours, imply that targeting the function of several key chemokines, but not many others, cou...

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Bibliographic Details
Main Authors: Nathan eKarin, Gizi eWildbaum
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Immunology
Subjects:
EAE
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00609/full