Higher initial DNA damage and persistent cell cycle arrest after carbon ion irradiation compared to X-irradiation in prostate and colon cancer cells.

Higher initial DNA damage and persistent cell cycle arrest after carbon ion irradiation compared to X-irradiation in prostate and colon cancer cells.

The use of charged particle beams such as carbon ions is becoming a more and more attractive treatment option for cancer therapy. Given the precise absorbed dose-localization and an increased biological effectiveness, this form of therapy is much more advantageous compared to conventional radiothera...

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Bibliographic Details
Main Authors: Annelies eSuetens, Katrien eKonings, Marjan eMoreels, Roel eQuintens, Mieke eVerslegers, Els eSoors, Kevin eTabury, Vincent eGrégoire, Sarah eBaatout
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Oncology
Subjects:
CaCo-2
cell cycle progression
PC3
Carbon ion irradiation
DNA double-strand break damage and repair
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00087/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00087/full

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