Defective bone repair in mast cell deficient mice with c-Kit loss of function

Defective bone repair in mast cell deficient mice with c-Kit loss of function

KitW-sh mice carry an inactivating mutation in the gene encoding the receptor for stem cell factor, which is expressed at high levels on the surface of haematopoietic precursor cells. The mutation results in mast cell deficiency, a variety of defects in innate immunity and poorly defined abnormaliti...

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Bibliographic Details
Main Authors: DA Behrends, L Cheng, MB Sullivan, MH Wang, GB Roby, N Zayed, C Gao, JE Henderson, PA Martineau
Format: Article
Language:English
Published: AO Research Institute Davos 2014-10-01
Series:European Cells & Materials
Subjects:
Osteo-immunology
c-Kit and mast cell deficiency
re-vascularisation
bone regeneration
Online Access:http://www.ecmjournal.org/journal/papers/vol028/pdf/v028a14.pdf

Internet

http://www.ecmjournal.org/journal/papers/vol028/pdf/v028a14.pdf

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