Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2)

Study protocol: a multi-centre randomised study of induction chemotherapy followed by capecitabine ± nelfinavir with high- or standard-dose radiotherapy for locally advanced pancreatic cancer (SCALOP-2)

Abstract Background Induction chemotherapy followed by chemoradiation is a treatment option for patients with locally advanced pancreatic cancer (LAPC). However, overall survival is comparable to chemotherapy alone and local progression occurs in nearly half of all patients, suggesting chemoradiatio...

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Bibliographic Details
Main Authors: Victoria Y. Strauss, Rachel Shaw, Pradeep S. Virdee, Christopher N. Hurt, Elizabeth Ward, Bethan Tranter, Neel Patel, John Bridgewater, Philip Parsons, Ganesh Radhakrishna, Eric O’Neill, David Sebag-Montefiore, Maria Hawkins, Pippa G. Corrie, Timothy Maughan, Somnath Mukherjee
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Cancer
Subjects:
Locally advanced pancreatic cancer (LAPC)
Chemoradiation
Gemcitabine and nab-paclitaxel (GEMABX)
Nelfinavir
Online Access:http://link.springer.com/article/10.1186/s12885-019-5307-z

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http://link.springer.com/article/10.1186/s12885-019-5307-z

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