Aspects of T Cell-Mediated Immunity Induced in Mice by a DNA Vaccine Based on the Dengue-NS1 Antigen after Challenge by the Intracerebral Route.

Aspects of T Cell-Mediated Immunity Induced in Mice by a DNA Vaccine Based on the Dengue-NS1 Antigen after Challenge by the Intracerebral Route.

Dengue disease has emerged as a major public health issue across tropical and subtropical countries. Infections caused by dengue virus (DENV) can evolve to life-threatening forms, resulting in about 20,000 deaths every year worldwide. Several animal models have been described concerning pre-clinical...

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Bibliographic Details
Main Authors: Edson R A Oliveira, Antônio J S Gonçalves, Simone M Costa, Adriana S Azevedo, Marcio Mantuano-Barradas, Ana Cristina M A Nogueira, Ada M B Alves
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5024998?pdf=render

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http://europepmc.org/articles/PMC5024998?pdf=render

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