Molecular pathways driving omeprazole nephrotoxicity

Molecular pathways driving omeprazole nephrotoxicity

Omeprazole, a proton pump inhibitor used to treat peptic ulcer and gastroesophageal reflux disease, has been associated to chronic kidney disease and acute interstitial nephritis. However, whether omeprazole is toxic to renal cells is unknown. Omeprazole has a lethal effect over some cancer cells, a...

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Bibliographic Details
Main Authors: Miguel Fontecha-Barriuso, Diego Martín-Sanchez, Julio M. Martinez-Moreno, Daniela Cardenas-Villacres, Susana Carrasco, Maria D. Sanchez-Niño, Marta Ruiz-Ortega, Alberto Ortiz, Ana B. Sanz
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:Redox Biology
Subjects:
Nephrotoxicity
Omeprazole
Oxidative stress
Cell death
Tubular proximal cells
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719316076

Internet

http://www.sciencedirect.com/science/article/pii/S2213231719316076

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