PGC-1α regulates alanine metabolism in muscle cells.

The skeletal muscle is the largest organ in the human body, depositing energy as protein/amino acids, which are degraded in catabolic conditions such as fasting. Alanine is synthesized and secreted from the skeletal muscle that is used as substrates of gluconeogenesis in the liver. During fasting, t...

Full description

Bibliographic Details
Main Authors: Yukino Hatazawa, Kun Qian, Da-Wei Gong, Yasutomi Kamei
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5760032?pdf=render