Insights into the Dichotomous Regulation of SOD2 in Cancer

While loss of antioxidant expression and the resultant oxidant-dependent damage to cellular macromolecules is key to tumorigenesis, it has become evident that effective oxidant scavenging is conversely necessary for successful metastatic spread. This dichotomous role of antioxidant enzymes in cancer...

Full description

Bibliographic Details
Main Authors: Yeon Soo Kim, Piyushi Gupta Vallur, Rébécca Phaëton, Karthikeyan Mythreye, Nadine Hempel
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/6/4/86