Inferring influenza infection attack rate from seroprevalence data.

Seroprevalence survey is the most practical method for accurately estimating infection attack rate (IAR) in an epidemic such as influenza. These studies typically entail selecting an arbitrary titer threshold for seropositivity (e.g. microneutralization [MN] 1∶40) and assuming the probability of ser...

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Main Authors: Joseph T Wu, Kathy Leung, Ranawaka A P M Perera, Daniel K W Chu, Cheuk Kwong Lee, Ivan F N Hung, Che Kit Lin, Su-Vui Lo, Yu-Lung Lau, Gabriel M Leung, Benjamin J Cowling, J S Malik Peiris
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-04-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3974861?pdf=render