m6A modification promotes miR-133a repression during cardiac development and hypertrophy via IGF2BP2

Abstract Both N6-methyladenosine (m6A) RNA modification and microRNAs (miRNAs) are common regulatory mechanisms for gene post-transcription by modulating mRNA stability and translation. They also share the same 3′-untranslated regions (UTRs) regions for their target gene. However, little is known ab...

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Bibliographic Details
Main Authors: Benheng Qian, Ping Wang, Donghong Zhang, Lianpin Wu
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00552-7