Transglutaminase 2 as a Marker for Inflammation and Therapeutic Target in Sepsis

Transglutaminase 2 as a Marker for Inflammation and Therapeutic Target in Sepsis

Sepsis results in lethal organ malfunction due to dysregulated host response to infection, which is a condition with increasing prevalence worldwide. Transglutaminase 2 (TG2) is a crosslinking enzyme that forms a covalent bond between lysine and glutamine. TG2 plays important roles in diverse cellul...

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Bibliographic Details
Main Authors: Ting Su, Xian-Yang Qin, Yutaka Furutani
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
transglutaminase
sepsis
antibacterial
antiviral
covalent crosslinking
inhibitor
Online Access:https://www.mdpi.com/1422-0067/22/4/1897

Internet

https://www.mdpi.com/1422-0067/22/4/1897

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